Incidence of Acute Myocardial Infarctions Up Among Young Women

MONDAY, Feb. 25, 2019 — The incidence of acute myocardial infarctions (AMI) has increased among younger women, and sedentary time is associated with an increased risk for cardiovascular disease (CVD) among women, according to two studies published in the Feb. 19 issue of Circulation, a “Go Red for Women” theme issue on cardiovascular disease in women.

Sameer Arora, M.D., from the University of North Carolina School of Medicine in Chapel Hill, and colleagues examined the incidence and risk factors of AMI among young patients using data from the Atherosclerosis Risk in Communities Surveillance study. The researchers observed an increase in the annual incidence of AMI hospitalizations among young women and a decrease among young men. In addition, young women had a lower probability of receiving lipid-lowering therapies, nonaspirin antiplatelets, beta-blockers, coronary angiography, and coronary revascularization.

John Bellettiere, M.P.H., Ph.D., from the University of California San Diego in La Jolla, and colleagues followed 5,638 women for up to 4.9 years for CVD events. The researchers identified 545 CVD events during 19,350 person-years. Women in the highest (about 11 hours or more per day) versus the lowest (about nine hours or less per day) quartile of sedentary time had an increased risk for CVD after adjustment for covariates (hazard ratio, 1.62).

“We hope that by highlighting some of the best research on cardiovascular disease in women, this issue of Circulation devoted to women’s heart health will ignite more interest in and greater commitment to conducting research in this area and propel relevant stakeholders to team up in the fight against cardiovascular disease in women,” Joseph A. Hill, M.D., Ph.D., editor-in-chief of Circulation, said in a statement.

Several authors from the Arora study disclosed financial ties to the pharmaceutical industry.

Abstract/Full Text – Arora
Editorial
Abstract/Full Text – Bellettiere

Posted: February 2019

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